反応式
[CH3:1][C:2]1[N:6]([CH2:7][CH:8]=[C:9]([CH3:11])[CH3:10])[C:5]([N+:12]([O-:14])=[O:13])=[N:4][CH:3]=1.[N+:15]([O-:23])(OCCC(C)C)=O.[ClH:24]>>[Cl:24][C:9]([CH3:11])([CH3:10])[CH:8]([N:15]=[O:23])[CH2:7][N:6]1[C:2]([CH3:1])=[CH:3][N:4]=[C:5]1[N+:12]([O-:14])=[O:13]参加物
4
実験手順
3-Chloro-3-methyl-2-nitroso-1-(5-methyl-2-nitro-1H-imidazol-1-yl) butane was prepared in 60% yield from 1-(5-methyl-2-nitro-1H-imidazol-1-yl)-3-methyl-2-butene (1.0 g, 5.12 mmol, Example 27), isoamyl nitrate (5.0 mL) and concentrated HCl (5.0 mL) following the procedure described for the preparation of its positional isomer (Example 27B) as a light blue solid; mp. 102-105° C. (decomp); 1H NMR (DMSO-d6) δ 1.73 [s, 6H, C(CH3)2], 2.32(s, 3H, imi-CH3), 5.53(s, 2H, NCH2), 6.97 ( s. 1H, imi-CH) and 11.58 (s, 1H, NOH). MS m/e 261 (M+H)+.
後処理
- customdescribed for the preparation of its positional isomer (Example 27B) as a light blue solid
出典と根拠
- ORDレコード
- ord-d4c52a84c0cd49e38b76c22e563f7c75
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06359120B1
関連ノート
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