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N-bromobutanimide → 3-Chloro-6-(3,5-dimethyl-4-bromo-1-pyrazolyl)-pyridazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | 3-Chloro-6-(3,5-dimethylpyrazol-1-yl)pyridazine | HCID 321073 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | 3-Chloro-6-(3,5-dimethyl-4-bromo-1-pyrazolyl)-pyridazine | HCID 12562844 | — |
反応手順
A mixture of 2.09 g (0.01 moles) of 3-chloro-6-(3,5-dimethyl-1-pyrazolyl)-pyridazine, 21 ml of carbon tetrachloride and 1.96 g (0.011 moles) of N-bromosuccinimide is boiled under stirring for 3 hours. After cooling the precipitate is filtered, washed with carbon tetrachloride and recrystallized from ethanol. Yield: 1.44 g (50.5%); m.p.: 143°-145° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04224325 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-b46bc50829b44cafb7981c0fd1a27fe7 |
| 出典メモ | uspto-grants-1980_09 |