Hydrochloric Acid → 3-(2-Hydroxyethylhydrazino)-6-(3,5-dimethyl-1-pyrazolyl)-pyridazine

HRID 27897

反応式

HRID 27897 の反応式
Cl[C:2]1[N:3]=[N:4][C:5]([N:8]2[C:12]([CH3:13])=[CH:11][C:10]([CH3:14])=[N:9]2)=[CH:6][CH:7]=1.[OH:15][CH2:16][CH2:17][NH:18][NH2:19].Cl>C(O)C>[OH:15][CH2:16][CH2:17][NH:18][NH:19][C:2]1[N:3]=[N:4][C:5]([N:8]2[C:12]([CH3:13])=[CH:11][C:10]([CH3:14])=[N:9]2)=[CH:6][CH:7]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 80172-HydrazinoethanolHCID 3210733-Chloro-6-(3,5-dimethylpyrazol-1-yl)pyridazine

生成物 1

HCID 540363033-(2-Hydroxyethylhydrazino)-6-(3,5-dimethyl-1-pyrazolyl)-pyridazine

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 2.09 g (0.01 moles) of 3-chloro-6-(3,5-dimethyl-1-pyrazolyl)-pyridazine, 30 ml of ethanol and 1.52 g (0.02 moles) of hydroxyethyl hydrazine is reacted and worked up in the same way as described in Example 42. Yield: 0.3 g (10.5%); the hydrochloride melts at 302°-305° C.

後処理

  1. customis reacted

出典と根拠

ORDレコード
ord-92350680f6dd4a6e8f7418eba77a39b7
出典データセット
uspto-grants-1980_09
特許番号
US04224325

関連ノート

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