Water → N-Methyl-N'-(5-methylpyridin-2-yl)thiourea

HRID 27904ノート

反応式

HRID 27904 の反応式
C(S[C:9](=[S:18])[NH:10][C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][N:12]=1)C1C=CC=CC=1.[CH3:19][NH2:20].O>C(O)C>[CH3:17][C:14]1[CH:15]=[CH:16][C:11]([NH:10][C:9]([NH:20][CH3:19])=[S:18])=[N:12][CH:13]=1

参加物

5

反応物 3

HCID 962WaterHCID 6329MethylamineHCID 71443099Benzyl (5-methylpyridin-2-yl)carbamodithioate

生成物 1

HCID 19686098N-Methyl-N'-(5-methylpyridin-2-yl)thiourea

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Benzyl(5-methyl-2-pyridyl)dithiocarbamate (3 g.) was suspended in ethanol (30 ml.). Methylamine (33% ethanolic solution, 10 ml.) was added and the mixture stirred at room temperature for 1 hour. On the addition of water, the thiourea separated and was collected by filtration, dried and recrystallised from ethanol-petrol ether. Yield 2.5 g., m.pt. 161° C.

後処理

  1. customthe thiourea separated
  2. filtrationwas collected by filtration
  3. customdried
  4. customrecrystallised from ethanol-petrol ether

出典と根拠

ORDレコード
ord-b97903e892bb4b40abd46fbd5d9cc700
出典データセット
uspto-grants-1980_09
特許番号
US04224331

反応ノート

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