Tributylphosphine → 7-(3-Benzyloxypropoxy)4-(4-chloro-2-fluoroanilino)-6-methoxyquinazoline hydrochloride

反応式

N(C(N1CCCCC1)=O)=NC(N1CCCCC1)=O.[Cl:19][C:20]1[CH:39]=[CH:38][C:23]([NH:24][C:25]2[C:34]3[C:29](=[CH:30][C:31]([OH:37])=[C:32]([O:35][CH3:36])[CH:33]=3)[N:28]=[CH:27][N:26]=2)=[C:22]([F:40])[CH:21]=1.[CH2:41]([O:48][CH2:49][CH2:50][CH2:51]O)[C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1.C(P(CCCC)CCCC)CCC>C(Cl)Cl.CCOCC>[ClH:19].[CH2:41]([O:48][CH2:49][CH2:50][CH2:51][O:37][C:31]1[CH:30]=[C:29]2[C:34]([C:25]([NH:24][C:23]3[CH:38]=[CH:39][C:20]([Cl:19])=[CH:21][C:22]=3[F:40])=[N:26][CH:27]=[N:28]2)=[CH:33][C:32]=1[O:35][CH3:36])[C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1