Hydrochloric Acid → 2,3-Dichloro-5-(trichloromethyl)pyridine

HRID 279738

反応式

HRID 279738 の反応式
Br[C:2]1[C:3]([Cl:9])=[N:4][CH:5]=[C:6](C)[CH:7]=1.[ClH:10].ClCl.[C:13]([Cl:17])(Cl)([Cl:15])[Cl:14]>>[Cl:9][C:3]1[C:2]([Cl:10])=[CH:7][C:6]([C:13]([Cl:17])([Cl:15])[Cl:14])=[CH:5][N:4]=1

参加物

5

反応物 4

HCID 313Hydrochloric AcidHCID 5943Carbon TetrachlorideHCID 24526ChlorineHCID 2854373-Bromo-2-chloro-5-methylpyridine

生成物 1

HCID 946472,3-Dichloro-5-(trichloromethyl)pyridine

実験手順

The product from (b) (64 g) in dry carbon tetrachloride (650 ml) was treated with dry hydrogen chloride. The precipitate was broken up and the suspension heated under reflux while dry chlorine was bubbled into the mixture, with illumination from an ultra-violet light source. After 41/2 hours, the mixture was cooled, filtered, and the filtrate evaporated to give the required 2,3-dichloro-5-trichloromethylpyridine. The mass spectrum was consistent with the structure assigned to this compound.

後処理

  1. temperaturethe suspension heated
  2. customwas bubbled into the mixture, with illumination from an ultra-violet light source
  3. temperatureAfter 41/2 hours, the mixture was cooled
  4. filtrationfiltered
  5. customthe filtrate evaporated

出典と根拠

ORDレコード
ord-2eba13a864c74495ba0de00f3e62458a
出典データセット
uspto-grants-1986_05
特許番号
US04586953

関連ノート

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