N-(3-bromophenyl)-3-oxobutanamide → HCID 178429223、化合物
反応式
[Br:1][C:2]1[CH:3]=[C:4]([NH:8][C:9](=[O:14])[CH2:10][C:11](=O)[CH3:12])[CH:5]=[CH:6][CH:7]=1>S(=O)(=O)(O)O>[OH:14][C:9]1[CH:10]=[C:11]([CH3:12])[C:5]2[C:4](=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=2)[N:8]=1参加物
3
実験手順
6.65 g (26.00 mM) of N-(3-bromophenyl)-3-oxobutyramide was heated in 30 mL of conc. sulfuric acid to 120° C. (oil bath temperature) for 1.5 h. The reaction mixture was then poured into ice, whereby precipitate was formed. This was filtered and washed repeatedly with water. After drying, it was recrystallised in 95% ethanol, providing 5.21 g (84%) of the product as a white solid: mp 275°-276° C.;
後処理
- additionThe reaction mixture was then poured into ice
- customwhereby precipitate was formed
- filtrationThis was filtered
- washwashed repeatedly with water
- customAfter drying
- customit was recrystallised in 95% ethanol
出典と根拠
- ORDレコード
- ord-a0b98b5ab3084f38a9a26fd3520d5c65
- 出典データセット
- uspto-grants-1986_05
- 特許番号
- US04587341
反応ノート
読み込み中…