化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2-(Methoxycarbonyl)thiophene-3-sulfonic acid | HCID 21431579 | — |
| 生成物 | 2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester | HCID 2736733 | — |
反応手順
7.4 G. of crude 3-sulfothiophene-2-carboxylic acid methyl ester are dissolved in 50 ml. of thionyl chloride and boiled to reflux for 16 hours. The mixture is then evaporated to dryness in vacuo and the remaining bright-yellow oil is brought to crystallization with petroleum ether. There is obtained 3-chlorosulfonylthiophene-2-carboxylic acid methyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04224445 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-f36a817170be4689979b6134143063af |
| 出典メモ | uspto-grants-1980_09 |