Phosphorus pentachloride → 3-Methoxy-2,2,3,3-tetrafluoropropionyl chloride

反応式

[CH3:1][O:2][C:3]([F:11])([F:10])[C:4]([F:9])([F:8])[C:5](O)=[O:6].P(Cl)(Cl)(Cl)(Cl)[Cl:13]>>[CH3:1][O:2][C:3]([F:11])([F:10])[C:4]([F:9])([F:8])[C:5]([Cl:13])=[O:6]

参加物

反応物 2

HCID 24819Phosphorus pentachloride

HCID 133289072,2,3,3-Tetrafluoro-3-methoxypropanoic acid

生成物 1

HCID 128460263-Methoxy-2,2,3,3-tetrafluoropropionyl chloride収率 95.2%

実験手順

A mixture of 47.4 g 3-methoxytetrafluoropropionic acid and 67.3 g phosphorous pentachloride was heated and the contents distilled to obtain a pale yellow liquid boiling to 102°. Redistillation of this liquid yielded 49.8 g (95.2%) 3-methoxytetrafluoropropionyl chloride, b.p. 84°-86°.

後処理

temperaturewas heated
distillationthe contents distilled
customto obtain a pale yellow liquid boiling to 102°
distillationRedistillation of this liquid

出典と根拠

ORDレコード: ord-fa8f90a5a9564181ae90cf68447d915a
出典データセット: uspto-grants-1986_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04590015

反応ノート

読み込み中…

参加物