Methanol → Salicylic acid, 4-nitro-, methyl ester

HRID 280832

反応式

HRID 280832 の反応式
[OH:1][C:2]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:14]O>S(=O)(=O)(O)O>[OH:1][C:2]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:3]=1[C:4]([O:6][CH3:14])=[O:5]

参加物

4

反応物 2

HCID 887MethanolHCID 692664-Nitrosalicylic acid

生成物 1

HCID 139539Salicylic acid, 4-nitro-, methyl ester

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

2-hydroxy-4-nitrobenzoic acid (25 g) was dissolved in 100 ml of methanol and sulfuric acid (11 ml, density 1.84). The solution was boiled for 24 hrs, whereupon it was poured onto ice water and extracted with chloroform. The chloroform phase was shaken against sodium hydrogen carbonate solution, dried with magnesium sulfate and evaporated. The product was crystallized from methanol. Yield: 21 g.

後処理

  1. additionwas poured onto ice water
  2. extractionextracted with chloroform
  3. dry with materialdried with magnesium sulfate
  4. customevaporated
  5. customThe product was crystallized from methanol

出典と根拠

ORDレコード
ord-5703b5d6de4b4f1faa1fd8a3a014c4fe
出典データセット
uspto-grants-1986_05
特許番号
US04591584

関連ノート

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