関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Triethyl phosphite | HCID 31215 | — |
| 反応物 | Carbonochloridic acid, 4-methoxyphenyl ester | HCID 82128 | — |
| 生成物 | Phosphinecarboxylic acid, diethoxy-, 4-methoxyphenyl ester, oxide | HCID 512114 | 89.5% |
反応手順
18.6 g (0.12 mole) of triethylphosphite was heated at 125°-130° C. in a flask with a reflux condensor. 18.6 g (0.10 mole) of 4-methoxyphenyl chloroformate (prepared according to M. J. Zabik and R. D. Schuetz, J. Org. Chem. 32 (1967) 300) was added dropwise. The reaction flask was heated additionally at about 120° C. for 1,5 hours and left at room temperature overnight. The product was distilled to give 25.8 g (89%) of diethyl 4-methoxyphenoxycarbonylphosphonate. Bp0.03 =174°-8° C., nD21 =1,4940.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04591583 |
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| 出典データセット | uspto-grants-1986_05 |
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| ORD ID | ord-40236d3b9b1d467a979626aef2869dff |
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| 出典メモ | uspto-grants-1986_05 |
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