Lithium Chloride → Benzonitrile, 2,3,6-trichloro-

HRID 28093ノート

反応式

HRID 28093 の反応式
[Cl:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[C:6]([N+]([O-])=O)[C:3]=1[C:4]#[N:5].[Cl-:14].[Li+].[Cl-].[Al+3].[Cl-].[Cl-]>CN1CCCC1=O>[Cl:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[C:6]([Cl:14])[C:3]=1[C:4]#[N:5]

参加物

5

反応物 3

HCID 433294Lithium ChlorideHCID 27360202,3-Dichloro-6-nitrobenzonitrileHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 3014307Benzonitrile, 2,3,6-trichloro-収率 91.9%

試薬・触媒・溶媒 1

HCID 13387N-methyl-2-pyrrolidone溶媒

実験手順

10.9 parts of 2,3-dichloro-6-nitrobenzonitrile, 0.84 parts of lithium chloride, 2.22 parts of anhydrous aluminum chloride and 15 parts of N-methyl-2-pyrrolidone were reacted at 180° C. for one hour, and the reaction solution was treated similarly to EXAMPLE B12 to obtain 9.4 parts of 2,3,6-trichlorobenzonitrile with purity of almost 100%. Yield: 91.9%.

後処理

  1. additionthe reaction solution was treated similarly to EXAMPLE B12

出典と根拠

ORDレコード
ord-559ca7f36b6e4ec28ab2984c9dcfbf89
出典データセット
uspto-grants-1980_09
特許番号
US04225534

反応ノート

読み込み中…