3-Bromothiophene → 1-(2-Ethyl-4-methyl-5-oxazolyl)-1-(3-thienyl)ethanol

反応式

Br[C:2]1[CH:6]=[CH:5][S:4][CH:3]=1.[C:7]([C:10]1[O:14][C:13]([CH2:15][CH3:16])=[N:12][C:11]=1[CH3:17])(=[O:9])[CH3:8]>>[CH2:15]([C:13]1[O:14][C:10]([C:7]([C:2]2[CH:6]=[CH:5][S:4][CH:3]=2)([OH:9])[CH3:8])=[C:11]([CH3:17])[N:12]=1)[CH3:16]

参加物

反応物 2

HCID 133833-Bromothiophene

HCID 189363281-(2-Ethyl-4-methyloxazol-5-yl)ethanone

生成物 1

HCID 189362931-(2-Ethyl-4-methyl-5-oxazolyl)-1-(3-thienyl)ethanol

実験手順

Starting with 3-bromothiophene and 5-acetyl-2-ethyl-4-methyloxazole and following the general method of Example 4 the title compound was prepared. M.p. 77.5°-79° C.

出典と根拠

ORDレコード: ord-e1ffdfaddb4c40e0b14bbab38f1940b1
出典データセット: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05731335

反応ノート

読み込み中…