Ammonia → Cyromazine

HRID 28111

反応式

HRID 28111 の反応式
[CH:1]1([NH:4][C:5]2[N:10]=[C:9](Cl)[N:8]=[C:7]([NH2:12])[N:6]=2)[CH2:3][CH2:2]1.[NH3:13]>O1CCOCC1>[CH:1]1([NH:4][C:5]2[N:10]=[C:9]([NH2:13])[N:8]=[C:7]([NH2:12])[N:6]=2)[CH2:3][CH2:2]1

参加物

4

反応物 2

HCID 222AmmoniaHCID 233389806-Chloro-N~2~-cyclopropyl-1,3,5-triazine-2,4-diamine

生成物 1

HCID 47866Cyromazine収率 55.8%

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

反応条件

温度
140 °C

実験手順

A mixture of 100 g of 2-cyclopropylamino-4-chloro-6-amino-s-triazine, 51 g of anhydrous ammonia and 500 ml of dioxane is heated for 24 hours in an autoclave at 140° C. After cooling to room temperature the solvent is removed by water jet vacuum distillation. 300 ml of water are added to the residue. After stirring, the residue product is filtered off and recrystallised from boiling ethanol. 50 g of 2-cyclopropylamino-4,6-diamino-s-triazine are obtained. Melting point: 219°-222° C.

後処理

  1. temperatureAfter cooling to room temperature the solvent
  2. customis removed by water jet vacuum distillation
  3. addition300 ml of water are added to the residue
  4. filtrationthe residue product is filtered off
  5. customrecrystallised

出典と根拠

ORDレコード
ord-1ea168a6fd874ae1beb21deef9846912
出典データセット
uspto-grants-1980_09
特許番号
US04225598

関連ノート

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