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Potassium Iodide → Ethyl 2-(p-chlorobenzylthio)-propionate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Iodide | HCID 4875 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Ethyl 2-bromopropionate | HCID 79040 | — |
| 反応物 | 4-Chlorobenzyl mercaptan | HCID 80409 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | Ethyl 2-(p-chlorobenzylthio)-propionate | HCID 20542836 | — |
反応手順
A mixture of 19.5 ml (0.15 mol) of 4-chlorobenzylmercaptan, 27.1 g (0.15 mol) of ethyl α-bromopropionate, 21 g of potassium carbonate and 0.1 g of potassium iodide in 100 ml of anhydrous acetone is kept under reflux for 6 hrs. It is filtered, the precipitate is washed with acetone and the filtrate is evaporated in vacuo. 200 ml of ether are added to the residue and the mixture is washed with dilute NaOH, dilute HCl and water, dried and evaporated in vacuo.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04225617 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-79fdbedb1756458194ee5fb490ea8b67 |
| 出典メモ | uspto-grants-1980_09 |