Acetate → Diethyl [(6-{[4-{[7-(trans-4-hydroxycyclohexyl)-2-methyl-3-oxo-2,3-dihydro-1H-isoindol-4-yl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-5-methoxypyridin-3-yl)methyl]phosphonate

HRID 282031

反応式

[C:49](=[O:50])([O-:51])[O-:52].[CH2:31]([CH3:32])[O:33][P:34]([O:35][CH2:36][CH3:37])(=[O:38])[CH2:39][c:40]1[cH:41][n:42][c:43]([NH2:48])[c:44]([O:46][CH3:47])[cH:45]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:27]([F:28])([F:29])[F:30])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([CH:20]3[CH2:21][CH2:22][CH:23]([OH:26])[CH2:24][CH2:25]3)[c:13]3[c:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14]3)[n:7]1.[Cs+:53].[Cs+:54].[O-:62][C:63]([CH3:64])=[O:65].[O-:66][C:67]([CH3:68])=[O:69].[O:55]1[CH2:56][CH2:57][O:58][CH2:59][CH2:60]1.[Pd+2:61]>>[c:2]1([NH:48][c:43]2[n:42][cH:41][c:40]([CH2:39][P:34]([O:33][CH2:31][CH3:32])([O:35][CH2:36][CH3:37])=[O:38])[cH:45][c:44]2[O:46][CH3:47])[n:3][cH:4][c:5]([C:27]([F:28])([F:29])[F:30])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([CH:20]3[CH2:21][CH2:22][CH:23]([OH:26])[CH2:24][CH2:25]3)[c:13]3[c:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14]3)[n:7]1