化工社化工社 化学情報印刷レポート · 研究参考用
Furfurylamine → 2-Amino-3-cyano-4-furfurylaminoquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Furfurylamine | HCID 3438 | — |
| 反応物 | 2-Amino-3-cyano4-chloroquinoline | HCID 11481121 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Amino-3-cyano-4-furfurylaminoquinoline | HCID 22273721 | 44.7% |
反応手順
10 g of 2-amino-3-cyano-4-chloroquinoline is heated with 19 g of furfurylamine at 120° C. for 3 hours. The reaction mixture is cooled to 25 C. and mixed 6 times with 50 ml of water. The crystals are filtered off and dried. The resulting product is recrystallized from 60 ml of N,N-dimethylformamide, to obtain 5.8 g of the title compound, m.p.: 206° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07419977B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-5bda3d78ea3743e7a3af617fb0032deb |
| 出典メモ | uspto-grants-2008_09 |