化工社化工社 化学情報印刷レポート · 研究参考用
Benzylamine → Acetoacetobenzylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzylamine | HCID 7504 | — |
| 反応物 | 2,2,6-Trimethyl-4H-1,3-dioxin-4-one | HCID 79368 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Acetoacetobenzylamide | HCID 70159 | — |
反応手順
9 ml (0.05 mol) of 2,2,6-trimethyl-4H-1,3-dioxin-4-one (diketene-acetone adduct) were added dropwise to a solution of 5.5 ml (0.05 mol) of benzylamine in 20 ml of toluene and the temperature was allowed to rise 70° C. The solution was refluxed for 2 h then the solvent was removed in vacuo. The crude product was triturated with ether obtaining 7.5 g of the title compound. M.p.=84°-86° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731322 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-f260c158922847e2b6dce05f84aaf68d |
| 出典メモ | uspto-grants-1998_03 |