化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylamine → Dimethylacetoacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | Diketene acetone | HCID 87118046 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Dimethylacetoacetamide | HCID 16278 | — |
反応手順
A solution of 9 ml (0.05 mmol) of diketene-acetone adduct in 20 ml of toluene was treated with gaseous dimethylamine at room temperature until the reaction was complete. The solvent was removed in vacuo and the residue was purified by chromatography on silica gel (EtOAc/MeOH 0%→10%) yielding 7.0 g of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731322 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-eb592b1203c74e969732293b7513ee02 |
| 出典メモ | uspto-grants-1998_03 |