化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → HCID 178418387、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Dimethylacetoacetamide | HCID 16278 | — |
| 反応物 | Benzenediazonium chloride | HCID 60992 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | HCID 178418387 | HCID 178418387 | 42.9% |
反応手順
4.5 g (0.035 mol) of N,N-dimethyl-3-oxobutyramide, a solution of 4.9 g (0.122 mol) of NaOH in 45 ml of water and 0.037 mol of phenyldiazonium chloride were treated as described in preparation 8. The crude reaction mixture was purified by chromatography on silica gel (hexane/Et2O 0%→100%) obtaining 3.5 g of the title compound which was used as such in the subsequent step. M.p.=131°-133° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731322 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-b070703fd73b4d8680fe6f71c91c67d7 |
| 出典メモ | uspto-grants-1998_03 |