化工社化工社 化学情報印刷レポート · 研究参考用
Water → HCID 178418328、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Benzenediazonium chloride | HCID 60992 | — |
| 反応物 | Ethyl 4,4,4-trifluoroacetoacetate | HCID 67793 | — |
| 反応物 | HCID 178418247 | HCID 178418247 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178418328 | HCID 178418328 | 60% |
反応手順
7.3 ml (0.05 mol) of ethyl 3-oxo-4,4,4-trifluoroacetoacetate, 6 g (0.073 mol) of CH3COONa, 20 ml of water, 37.5 ml of ethanol and a solution of 0.05 mol of phenyldiazonium chloride were treated as described in preparation 2. The crude product was purified by chromatography on silica gel (hexane/Et2O 0%→25%) obtaining 8.65 g of the title compound. M.p.=78°-80° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731322 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-5378909b6f194efbaaaae9d5077f9d43 |
| 出典メモ | uspto-grants-1998_03 |