2-Amino-5-fluoro-N-methylbenzamide → Diethyl [4-({4-[(1,3-dimethyl-4-oxo-1,4-dihydroquinolin-5-yl)amino]-5-(trifluoromethyl)pyrimidin-2-yl}amino)-3-methoxybenzyl]phosphonate

反応式

[Cl:13][c:14]1[n:15][c:16]([NH:24][c:25]2[c:26]([O:40][CH3:41])[cH:27][c:28]([CH2:29][P:30]([O:31][CH2:32][CH3:33])([O:34][CH2:35][CH3:36])=[O:37])[cH:38][cH:39]2)[n:17][cH:18][c:19]1[C:20]([F:21])([F:22])[F:23].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:6])[cH:7][c:8]1[C:9]([NH:10][CH3:11])=[O:12].[NH2:42][c:43]1[c:44]2[c:45](=[O:55])[c:46]([CH3:54])[cH:47][n:48]([CH3:53])[c:49]2[cH:50][cH:51][cH:52]1>>[c:14]1([NH:42][c:43]2[c:44]3[c:45](=[O:55])[c:46]([CH3:54])[cH:47][n:48]([CH3:53])[c:49]3[cH:50][cH:51][cH:52]2)[n:15][c:16]([NH:24][c:25]2[c:26]([O:40][CH3:41])[cH:27][c:28]([CH2:29][P:30]([O:31][CH2:32][CH3:33])([O:34][CH2:35][CH3:36])=[O:37])[cH:38][cH:39]2)[n:17][cH:18][c:19]1[C:20]([F:21])([F:22])[F:23]