Dimethyl Sulfoxide → 2-Chloro-4-(3-hydroxy-2-methylpyrrolidin-1-yl)-5-methylbenzonitrile

反応式

[CH3:26][S:27](=[O:28])[CH3:29].[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([CH3:11])[c:8]([F:10])[cH:9]1.[Li+:19].[Li+:20].[O-:21][C:22](=[O:23])[O-:24].[OH2:25].[OH:12][CH:13]1[CH:14]([CH3:18])[NH:15][CH2:16][CH2:17]1>>[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([CH3:11])[c:8]([N:15]2[CH:14]([CH3:18])[CH:13]([OH:12])[CH2:17][CH2:16]2)[cH:9]1