Water → N-cyclohexylidene-2,6-dimethoxy-4-methylaniline

HRID 2917

反応式

HRID 2917 の反応式
[CH3:1][O:2][C:3]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([O:11][CH3:12])[C:4]=1[NH2:5].[C:13]1(=O)[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1.O>C1(C)C=CC=CC=1>[C:13]1(=[N:5][C:4]2[C:6]([O:11][CH3:12])=[CH:7][C:8]([CH3:10])=[CH:9][C:3]=2[O:2][CH3:1])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

参加物

5

反応物 3

HCID 962WaterHCID 7967CyclohexanoneHCID 124090902,6-Dimethoxy-4-methylaniline

生成物 1

HCID 18936522N-cyclohexylidene-2,6-dimethoxy-4-methylaniline

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

4.2 g of 2,6-dimethoxy-4-methylaniline are dissolved in 50 ml of toluene, 2.45 g of cyclohexanone are then added and the reaction mixture is heated at reflux for 18 hours. The water which is formed is removed as it is formed in the reaction mixture using a Dean and Stark apparatus. The toluene is evaporated and the oily N-cyclohexylidene-2,6-dimethoxy-4-methylaniline residue obtained is used without addition of purification in the following stage.

後処理

  1. temperaturethe reaction mixture is heated
  2. temperatureat reflux for 18 hours
  3. customis removed as it
  4. customis formed in the reaction mixture
  5. customThe toluene is evaporated

出典と根拠

ORDレコード
ord-7722dbce85914723bdf979fd6d719ccd
出典データセット
uspto-grants-1998_03
特許番号
US05731340

関連ノート

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