Dimethyl Sulfoxide → 2-Chloro-3-fluoro-4-[3-(2-hydroxypropan-2-yl)-2-methylpyrrolidin-1-yl]benzonitrile

反応式

[CH3:28][S:29](=[O:30])[CH3:31].[Cl:11][c:12]1[c:13]([C:14]#[N:15])[cH:16][cH:17][c:18]([F:21])[c:19]1[F:20].[Li+:22].[Li+:23].[O-:24][C:25](=[O:26])[O-:27].[OH:1][C:2]([CH3:3])([CH3:4])[CH:5]1[CH:6]([CH3:10])[NH:7][CH2:8][CH2:9]1>>[OH:1][C:2]([CH3:3])([CH3:4])[CH:5]1[CH:6]([CH3:10])[N:7]([c:18]2[cH:17][cH:16][c:13]([C:14]#[N:15])[c:12]([Cl:11])[c:19]2[F:20])[CH2:8][CH2:9]1