3-Methyl-4-phenyl-benzofuran-2-carboxylic acid tert-butyl ester → 3-Methyl-4-phenyl-benzofuran-2-carboxylic acid
反応式
C([O:5][C:6]([C:8]1[O:9][C:10]2[CH:17]=[CH:16][CH:15]=[C:14]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:11]=2[C:12]=1[CH3:13])=[O:7])(C)(C)C>C(O)(C(F)(F)F)=O.ClCCl>[CH3:13][C:12]1[C:11]2[C:14]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:15][CH:16]=[CH:17][C:10]=2[O:9][C:8]=1[C:6]([OH:7])=[O:5]参加物
3
実験手順
3-Methyl-4-phenyl-benzofuran-2-carboxylic acid tert-butyl ester was dissolved in 2 mL of TFA/dichloromethane (1:1). The solution was stirred at room temperature for 3 h. The solvents were removed under vacuum and the residue was triturated with ether. Filtration gave 66 mg of 3-methyl-4-phenyl-benzofuran-2-carboxylic acid as white solid.
後処理
- customThe solvents were removed under vacuum
- customthe residue was triturated with ether
- filtrationFiltration
出典と根拠
- ORDレコード
- ord-e1ab8c4507624175b4daebc0b85570af
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07420001B2
反応ノート
読み込み中…