5-Methyl-thiophene-2-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amide → 2-Chloromethyl-N-[4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl]-isonicotinamide

HRID 294217

反応式

[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:7]2[c:8]1[n:9][c:10]([NH2:12])[s:11]2.[Cl:19][CH2:20][c:21]1[cH:22][c:23]([C:24](=[O:25])[OH:26])[cH:27][cH:28][n:29]1.[O:30]1[CH2:31][CH:32]([c:33]2[c:34]3[s:35][c:36]([NH:37][C:38]([c:39]4[s:40][c:41]([CH3:42])[cH:43][cH:44]4)=[O:45])[n:46][c:47]3[c:48]([O:49][CH3:50])[cH:51][cH:52]2)[CH2:53][O:54][CH2:55][CH2:56]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:7]2[c:8]1[n:9][c:10]([NH:12][C:24]([c:23]1[cH:22][c:21]([CH2:20][Cl:19])[n:29][cH:28][cH:27]1)=[O:25])[s:11]2