化工社化工社 化学情報印刷レポート · 研究参考用
2-Phenylisobutyric acid → 2-Methyl-2-phenylpropanoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Phenylisobutyric acid | HCID 13222 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2-Methyl-2-phenylpropanoyl chloride | HCID 12369086 | — |
反応手順
A solution of 2-Methyl-2-phenylpropionic acid (10 mmol, 1.0 eq.) and oxalyl chloride (40 mmol, 4.0 eq.) in dichloromethane (30 mL) was stirred at room temperature for 18 h. The mixture was concentrated in vacuo to afford the title compound as a yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07420055B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-b388f55835f0450eb8040b6671d8a7a3 |
| 出典メモ | uspto-grants-2008_09 |