4-Methanesulfonylbenzene-1-sulfonyl chloride → N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]4-methanesulfonyl-benzenesulfonamide

関与物質

反応手順

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 116 mg of (2-amino-5-chloro-phenyl)-pyridin-4-yl-methanone and 127 mg of 4-methanesulfonyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 3.06 (s, 3H), 7.31 (d, 1H, J=2.0 Hz), 7.45 (m, 2H), 7.58 (dd, 1H, J=8.8 Hz, 2.8 Hz), 7.99 (b, 4H), 8.88 (dd, 2H, J=4.8 Hz, 1.6 Hz), 10.29 (b,1H). MS: m/z 451.9 (M++1).

情報源と証拠