Tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate → Isopropyl 4-(5-chloro-1-(4-cyano-3-fluorophenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate

HRID 295629

反応式

[CH3:32][S:33]([c:34]1[cH:35][cH:36][c:37](-[n:38]2[cH:39][cH:40][c:41]([O:42][CH:43]3[CH2:44][CH2:45][N:46]([C:47]([O:48][C:49]([CH3:50])([CH3:51])[CH3:52])=[O:53])[CH2:54][CH2:55]3)[cH:56][c:57]2=[O:58])[cH:59][cH:60]1)(=[O:61])=[O:62].[Cl:1][c:2]1[c:3]([O:18][CH:19]2[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]2)[cH:4][c:5](=[O:17])[n:6](-[c:8]2[cH:9][c:10]([F:16])[c:11]([C:14]#[N:15])[cH:12][cH:13]2)[cH:7]1.[Cl:63][C:64]([O:65][CH:66]([CH3:67])[C:68]([F:69])([F:70])[F:71])=[O:72]>>[Cl:1][c:2]1[c:3]([O:18][CH:19]2[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][CH:28]([CH3:29])[CH3:30])[CH2:23][CH2:24]2)[cH:4][c:5](=[O:17])[n:6](-[c:8]2[cH:9][c:10]([F:16])[c:11]([C:14]#[N:15])[cH:12][cH:13]2)[cH:7]1