反応式
[OH:1][C:2]1[CH:10]=[C:9]([O:11][CH2:12][CH2:13][O:14][N:15]=[C:16]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH3:17])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[C:24]1([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH:29]=[CH:28][C:27]([C:30](Cl)=[O:31])=[CH:26][CH:25]=1>>[C:24]1([C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH:25]=[CH:26][C:27]([C:30]([O:1][C:2]2[CH:10]=[C:9]([O:11][CH2:12][CH2:13][O:14]/[N:15]=[C:16](/[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)\[CH3:17])[CH:8]=[CH:7][C:3]=2[C:4]([OH:6])=[O:5])=[O:31])=[CH:28][CH:29]=1参加物
3
実験手順
The title compound was prepared as a white solid (0.076 g, 40%) from 2-hydroxy-4-[2-({[1-phenylethylidene]amino}oxy)ethoxy]benzoic acid and biphenyl-4-carbonyl chloride using a procedure similar to example 8. mp=157.5-159.1° C.; mass spectrum (+EI, M+) m/z 495. 1H NMR (400 MHz, DMSO-d6); δ 12.67 (s, 1H), 8.14 (d, 2H), 7.93 (d, 1H), 7.88 (d, 1H), 7.78 (d, 2H), 7.65 (dd, 2H), 7.52 (dd, 2H), 7.45 (dd, 1H), 7.38 (s, 1H), 7.36 (d, 2H), 7.04 (dd, 1H), 7.02 (s, 1H), 4.47(t, 2H), 4.40 (t, 2H), 2.17 (s, 3H). Elemental analysis: Calcd. for C30H25NO6: C, 70.72H, 5.09; N, 2.83, Found: C, 70.92; H, 4.92; N, 2.76.
出典と根拠
- ORDレコード
- ord-50f8cff905c74100bc7135b77ab93b73
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07420083B2
関連ノート
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