化工社化工社 化学情報印刷レポート · 研究参考用
4-Toluenesulfonyl chloride → 3-iodo-N,4-dimethylbenzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 反応物 | 3-Iodo-4-methylbenzoic acid | HCID 621640 | — |
| 反応物 | Methylamine hydrochloride | HCID 6364545 | — |
| 生成物 | 3-iodo-N,4-dimethylbenzamide | HCID 19688440 | — |
反応手順
A solution of 1.0 mmol of 3-iodo-4-methylbenzoic acid, 1.2 mmol of TsCl, and 25 mmol of Py was stirred for 3 h and then 5 mmol of methylamine hydrochloride was added and stirring continued for 5 h. Chromatography provided N-methyl-(3-iodo-4-methylphenyl)carboxamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731432 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-d5a686fbf7b9481c9a917b96b78bc8ab |
| 出典メモ | uspto-grants-1998_03 |