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Formic Acid → N-formylphenylalanine methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Formic Acid | HCID 284 | — |
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Methyl L-phenylalaninate hydrochloride | HCID 75736 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | N-formylphenylalanine methyl ester | HCID 7016392 | — |
反応手順
To a mixture of 1 mmol of phenylalanine methyl ester hydrochloride and 2 mmol of triethylamine in 1 mL of DMF at 0 ° C. was added 2 mL of formic acid and 0.7 mL of acetic anhydride. After stirring for 16 h at rt, extractive isolation provided N-formylphenylalanine methyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731432 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-2f2ad81b1f6b433ea7c984999ad32978 |
| 出典メモ | uspto-grants-1998_03 |