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Iodine → 3-Iodo-4-methylbenzyl alcohol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | 3-Iodo-4-methylbenzoic acid | HCID 621640 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 3-Iodo-4-methylbenzyl alcohol | HCID 5166798 | — |
反応手順
A mixture of 1.0 mmol of 3-iodo-4-methylbenzoic acid and 1.2 mmol of NaBH4 in 4 mL of anhydrous THF was stirred for 30 min and then 0.5 mmol of iodine in 2.0 mL of THF at 5° C. was added. After stirring for 2 h the mixture was processed by extraction to provide 3-iodo-4-methylbenzyl alcohol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731432 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-2717ca80753c46a39e12e91d075435b5 |
| 出典メモ | uspto-grants-1998_03 |