関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tert-Butylamine | HCID 6385 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Silane, (chloromethyl)trimethyl- | HCID 75361 | — |
| 生成物 | N-tert-Butyl-N-(trimethylsilylmethyl)amine | HCID 425246 | — |
反応手順
A mixture of tert-butylamine (18.0 mL, 171 mmol) and (chloromethyl)trimethylsilane (7.00 g, 57.1 mmol) was heated in a thick-walled glass tube at 200° C. overnight. After cooling to ambient temperature, the reaction mixture was poured into 1 N NaOH and extracted three times with diethyl ether. The combined organic extracts were washed with brine, dried (MgSO4), and the volatiles evaporated in vacuo. Distillation (atmospheric pressure; ˜135° C.) of the residual liquid gave the title compound 77 as a colorless liquid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07419990B2 |
|---|
| 出典データセット | uspto-grants-2008_09 |
|---|
| ORD ID | ord-043b0c3cc51046faa4d80dcc8ff53bfc |
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| 出典メモ | uspto-grants-2008_09 |
|---|
