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Ethanol → N-(3-{[(4-aminophenyl)amino]methyl}benzyl)benzene-1,4-diamine tetrahydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Ammonium Chloride | HCID 25517 | — |
| 反応物 | 4-nitro-N-(3-{[(4-nitrophenyl)amino]methyl}benzyl)aniline | HCID 58794783 | — |
| 触媒 | Zinc | HCID 23994 | — |
| 溶媒 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 生成物 | N-(3-{[(4-aminophenyl)amino]methyl}benzyl)benzene-1,4-diamine tetrahydrochloride | HCID 69255182 | — |
反応手順
The mixture of powdered zinc (30 g), ammonium chloride (3 g), water (5 ml) and absolute ethanol were brought to reflux with the oil bath. The 4-nitro-N-(3-{[(4-nitrophenyl)amino]methyl}benzyl)aniline (3 g) was dissolved in 50 ml of NMP and introduced dropwise until there was decoloration of the reaction medium, while at the same time the reflux was maintained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07422609B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-6d2e4894e5894decb1f5ef3468560367 |
| 出典メモ | uspto-grants-2008_09 |