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3-Iodo-4-methylbenzaldehyde → 3-Iodo-4-methylstyrene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Iodo-4-methylbenzaldehyde | HCID 12330254 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 触媒 | Methyltriphenyliphosphonium bromide | HCID 74505 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 3-Iodo-4-methylstyrene | HCID 19688424 | — |
反応手順
This aldehyde (1 mmol)was added to a premixed solution of 1.5 mmol of methyl triphenylphosphonium bromide and 1.2 mmol of n-BuLi in 5 mL of THF at 0° C. and this mixture was stirred for 3-6 h at rt and then processed by extraction and chromatography to give 3-iodo-4-methylstyrene.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731432 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-e65eb05600a341c1a97cfb8e1984da81 |
| 出典メモ | uspto-grants-1998_03 |