4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine → N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(6-ethynyl-2-oxoquinolin-1(2H)-yl)acetamide

反応式

[Br:18][c:19]1[c:20](-[c:25]2[n:26][cH:27][n:28][nH:29]2)[c:21]([NH2:24])[s:22][cH:23]1.[C:1](#[CH:2])[c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](=[O:17])[n:9]([CH2:13][C:14](=[O:15])[OH:16])[c:10]2[cH:11][cH:12]1>>[C:1](#[CH:2])[c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](=[O:17])[n:9]([CH2:13][C:14](=[O:16])[NH:24][c:21]3[c:20](-[c:25]4[n:26][cH:27][n:28][nH:29]4)[c:19]([Br:18])[cH:23][s:22]3)[c:10]2[cH:11][cH:12]1

参加物

反応物 2

HCID 596366864-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine

HCID 866494242-(6-Ethynyl-2-oxoquinolin-1(2H)-yl)acetic acid

生成物 1

HCID 59636680N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(6-ethynyl-2-oxoquinolin-1(2H)-yl)acetamide

出典と根拠

ORDレコード: ord-b972777a85144425904fbf3789f99d81
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…