関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 3-Bromo-4-fluorobenzaldehyde | HCID 173604 | — |
| 触媒 | HCID 178418397 | HCID 178418397 | — |
| 生成物 | Methyl 3-carbomethoxy-4-fluorobenzaldehyde | HCID 19688468 | — |
反応手順
A mixture of 1.0 mmol of 3-bromo-4-fluorobenzaldehyde, 4 mL of DMF, 0.2 mL of triethylamine, 0.4 mL of MeOH and 0.05 mmol of Pd(PPh3)4 was heated at 90° C. at 40 psi under CO atmosphere for 16 h. Extraction and chromatography provided methyl 3-carbomethoxy-4-fluorobenzaldehyde.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05731432 |
|---|
| 出典データセット | uspto-grants-1998_03 |
|---|
| ORD ID | ord-d9642a5bf49d4ae5ab36a31093ec85a4 |
|---|
| 出典メモ | uspto-grants-1998_03 |
|---|
