5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine → 5-{3-[4-(3,4-Dichloro-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-phenyl}-pyridin-2-ylamine

反応式

[Br:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([C:22]([F:23])([F:24])[F:25])[cH:11][c:12](-[c:14]3[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]3)[n:13]2)[cH:5][cH:6][cH:7]1.[NH2:26][c:27]1[n:28][cH:29][c:30]([B:33]2[O:34][C:35]([CH3:36])([CH3:37])[C:38]([CH3:39])([CH3:40])[O:41]2)[cH:31][cH:32]1>>[c:2]1(-[c:30]2[cH:29][n:28][c:27]([NH2:26])[cH:32][cH:31]2)[cH:3][c:4](-[c:8]2[n:9][c:10]([C:22]([F:23])([F:24])[F:25])[cH:11][c:12](-[c:14]3[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]3)[n:13]2)[cH:5][cH:6][cH:7]1

参加物

反応物 2

HCID 27565555-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

HCID 574687552-(3-Bromo-phenyl)-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine

生成物 1

HCID 602093855-{3-[4-(3,4-Dichloro-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-phenyl}-pyridin-2-ylamine

出典と根拠

ORDレコード: ord-7cd163a05a8e43558cc4cb72c825fe64
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…