化工社化工社 化学情報印刷レポート · 研究参考用
Sodium hydride → Trimethylsilylethoxymethyltetrazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 2-Chloromethyl 2-(trimethylsilyl)ethyl ether | HCID 2724271 | — |
| 反応物 | HCID 178418441 | HCID 178418441 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Trimethylsilylethoxymethyltetrazole | HCID 178418485 | — |
反応手順
To a Suspension of 1.1 mmol NaH in 5 mL DMF at 0° C. was added a solution of 1.0 mmol tetrazole in 2 mL DMF. After 30 min, trimethylsilylethoxymethylchloride was added and the mixture stirred for 16 h. Extraction and chromatography provided trimethylsilylethoxymethyltetrazole as an oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05731432 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-dfbffeb92a874b419566deb178159f88 |
| 出典メモ | uspto-grants-1998_03 |