化工社化工社 化学情報印刷レポート · 研究参考用
4-Methoxybenzohydrazide → HCID 178491626、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methoxybenzohydrazide | HCID 76792 | — |
| 反応物 | Ethanimidic acid, ethyl ester, hydrochloride (1:1) | HCID 2724290 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178491626 | HCID 178491626 | — |
反応手順
4.6 g (0.20 mol) sodium in 200 mL ethanol are combined at ambient temperature with a solution of 25 g (0.20 mol) ethyl acetimidate hydrochloride in 200 mL ethanol. The sodium chloride precipitated is suction filtered and 33.2 g (0.20 mol) 4-methoxybenzoic acid hydrazide are added to the filtrate. The reaction mixture is stirred overnight at ambient temperature and then cooled. The precipitate formed is separated off and washed with ethanol and diethyl ether. Yield: 33.6 g (81%); melting range=179-181° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07423036B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-6ce67abe01174be09ba2b5676c9ac2f4 |
| 出典メモ | uspto-grants-2008_09 |