Acetic Acid → 2-(4-Aminophenoxy)-2-methylpropanoic acid

HRID 2988

反応式

HRID 2988 の反応式
[NH:1]([C:5]1[CH:17]=[CH:16][C:8]([O:9][C:10]([CH3:15])([CH3:14])[C:11]([OH:13])=[O:12])=[CH:7][CH:6]=1)C(C)=O.C(O)(=O)C>[OH-].[K+]>[NH2:1][C:5]1[CH:6]=[CH:7][C:8]([O:9][C:10]([CH3:15])([CH3:14])[C:11]([OH:13])=[O:12])=[CH:16][CH:17]=1

参加物

4

反応物 2

HCID 176Acetic AcidHCID 148798552-(4-Acetamidophenoxy)-2-methylpropanoic acid

生成物 1

HCID 27749582-(4-Aminophenoxy)-2-methylpropanoic acid収率 62%

試薬・触媒・溶媒 1

HCID 14797Potassium Hydroxide溶媒

実験手順

1.18 g (0.005 mol) of the 2-(4-acetaminophenoxy)-2-methyl propionic acid is boiled in 10% KOH (60 ml) for 1/2 hour. The solution is then cooled and acidified with acetic acid to yield 0.6 g (62% yield) of 2-(4-aminophenoxy)-2-methyl propionic acid as a yellowish white powder, mp 214°-16° C.

後処理

  1. temperatureThe solution is then cooled

出典と根拠

ORDレコード
ord-5df4ba9dfa614b57afe5f1e9bd2ce8ad
出典データセット
uspto-grants-1998_03
特許番号
US05731454

関連ノート

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