関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tyrosol | HCID 10393 | — |
| 反応物 | (Chloromethyl)cyclopropane | HCID 80013 | — |
| 反応物 | Potassium tert-butoxide | HCID 23665647 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 4-[2-(Cyclopropylmethoxy)ethyl]phenol | HCID 11052481 | — |
反応手順
A reaction flask was charged with 4-Hydroxyphenethyl alcohol (1) (100 g, 0.72 mol), Potassium tert-butoxide (243 g, 2.17 mol), and 500 mL of DMSO. The mixture was stirred under nitrogen at 50° C. for 30 minutes. A solution of (Chloromethyl)cyclopropane (100 g, 1.10 mol) in 500 mL of DMSO was added dropwise to the reaction mixture. The mixture was then stirred at 50° C. for one hour and then cooled to room temperature.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05731463 |
|---|
| 出典データセット | uspto-grants-1998_03 |
|---|
| ORD ID | ord-01039e4c25c144fb9c3dd548ff4937c0 |
|---|
| 出典メモ | uspto-grants-1998_03 |
|---|
