Phosphorus oxychloride → 1-Chloro-4-cyclopentyl-7-methoxyphthalazine
反応式
[CH:1]1([C:6]2[C:15]3[C:10](=[CH:11][C:12]([O:16][CH3:17])=[CH:13][CH:14]=3)[C:9](=O)[NH:8][N:7]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.P(Cl)(Cl)([Cl:21])=O>>[Cl:21][C:9]1[C:10]2[C:15](=[CH:14][CH:13]=[C:12]([O:16][CH3:17])[CH:11]=2)[C:6]([CH:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[N:7][N:8]=1参加物
3
実験手順
This compound is obtained according to the procedure described in 1.3. by reacting 4-cyclopentyl-7-methoxy-2H-phthalazin-1-one with phosphoryl chloride. The product is too impure for a description by NMR. It is used as obtained in the following amination reaction.
後処理
- customThis compound is obtained
- customas obtained in the
- customfollowing amination reaction
出典と根拠
- ORDレコード
- ord-98b16decaa6b48368c3a5825c80b03eb
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07423030B2
反応ノート
読み込み中…