2-Bromo-5-methoxybenzoic acid → 2-(2,5-Dimethoxybenzoyl)-5-methoxybenzoic acid

HRID 30020ノート

反応式

HRID 30020 の反応式
Br[C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C([Li])CCC.[CH3:18][O:19][C:20]1[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[CH:28][C:21]=1[C:22](N(OC)C)=[O:23]>>[CH3:18][O:19][C:20]1[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[CH:28][C:21]=1[C:22]([C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])=[O:23]

参加物

4

反応物 3

HCID 899062-Bromo-5-methoxybenzoic acidHCID 18931310N,2,5-trimethoxy-N-methylbenzamideHCID 178418339Butyllithium

生成物 1

HCID 692122442-(2,5-Dimethoxybenzoyl)-5-methoxybenzoic acid

実験手順

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 2,5-dimethoxy-N-methoxy-N-methylbenzamide. It is crystallized from diisopropyl ether.

後処理

  1. customThis compound is synthesized
  2. customIt is crystallized from diisopropyl ether

出典と根拠

ORDレコード
ord-dd638509591b49f5843084af3c32ff33
出典データセット
uspto-grants-2008_09
特許番号
US07423030B2

反応ノート

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