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HRID 30108作成日：2026年10月25日

[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate → [2-Amino-6-(1-methanesulfonyl-piperidin4-ylamino)-pyridin-3-yl]-(2-fluoro-phenyl)-methanone

https://huagongshe.com/reaction/30108

反応式

関与物質

役割名称HCID仕込み量
反応物[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetateHCID 11975076—
反応物(2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanoneHCID 58590830—
生成物[2-Amino-6-(1-methanesulfonyl-piperidin4-ylamino)-pyridin-3-yl]-(2-fluoro-phenyl)-methanoneHCID 11610846—

反応手順

The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone (Example 7) and 1-methanesulfonyl-piperidin-4-ylamine (Step A, Example 6) using the procedure described in Step B. Example 6. HRMS, observed: 392.1329, calcd for M+: 392.1318.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07423051B2
出典データセットuspto-grants-2008_09
ORD IDord-d4d179e4f6114701810dd15f310df06f
出典メモuspto-grants-2008_09