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1-Benzyl-4-piperidylamine → [2-Amino-6-(1-benzyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-phenyl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Benzyl-4-piperidylamine | HCID 415852 | — |
| 反応物 | (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanone | HCID 58590829 | — |
| 生成物 | [2-Amino-6-(1-benzyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-phenyl)-methanone | HCID 11704736 | — |
反応手順
The title compound was prepared from (2-amino-6-chloropyridin-3-yl)-(5-fluoro-2-methoxyphenyl)methanone (Example 19) and 4-amino-1-benzylpiperidine (Ardrich) using the procedure described in Step B. Example 6. HRMS, observed: 435.2196, Calcd for (M+H)+: 435.2191.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07423051B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-e92a58b2d5ae4f7783e882274bab8338 |
| 出典メモ | uspto-grants-2008_09 |