Isobutyric anhydride → methyl(11R,12S,13E,15S,17R)-9-isobutyryloxy-11,15-bis(tert-butyldimethylsiloxy)-17,20-dimethyl-7-thiaprosta-8,13-dienoate

反応式

I/[CH:2]=[CH:3]/[C@@H:4]([O:12][Si:13]([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:15])[CH3:14])[CH2:5][C@H:6]([CH3:11])[CH2:7][CH2:8][CH2:9][CH3:10].[C:20]([Li])([CH3:23])([CH3:22])[CH3:21].C([Cu])#CCCCC.C([C@H:36]1[CH2:40][C:39](=[O:41])[C:38]([S:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][C:48]([O:50][CH3:51])=[O:49])=[C:37]1O[SiH](C)C)(C)(C)C.[C:56]([O:61]C(=O)C(C)C)(=O)[CH:57]([CH3:59])[CH3:58]>CN(C)P(N(C)C)N(C)C>[CH3:51][O:50][C:48](=[O:49])[CH2:47][CH2:46][CH2:45][CH2:44][CH2:43][S:42][C:38]1[C@@H:37](/[CH:2]=[CH:3]/[C@@H:4]([O:12][Si:13]([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:15])[CH3:14])[CH2:5][C@H:6]([CH3:11])[CH2:7][CH2:8][CH2:9][CH3:10])[C@H:36]([O:12][Si:13]([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:15])[CH3:14])[CH2:40][C:39]=1[O:41][C:56](=[O:61])[CH:57]([CH3:59])[CH3:58]