4-Amino-5-chloro-2-methoxybenzoic acid → 4-amino-5-chloro-N-(1-(3-(2,3-dihydro-1,3-dioxo-1 H-isoindol-2-yl)propyl)-pyrrolidin-3-ylmethyl)-2-methoxybenzamide

反応式

[C:1]([O:2][C:6](=[O:7])[NH:8][CH2:9][CH:10]1[CH2:11][N:12]([CH2:15][CH2:16][CH2:17][N:18]2[C:19](=[O:28])[c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]3[C:26]2=[O:27])[CH2:13][CH2:14]1)([CH3:3])([CH3:4])[CH3:5].[NH2:29][c:30]1[cH:31][c:32]([O:40][CH3:41])[c:33]([C:34]([OH:35])=[O:36])[cH:37][c:38]1[Cl:39]>>[C:6](=[O:7])([NH:8][CH2:9][CH:10]1[CH2:11][N:12]([CH2:15][CH2:16][CH2:17][N:18]2[C:19](=[O:28])[c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]3[C:26]2=[O:27])[CH2:13][CH2:14]1)[c:33]1[c:32]([O:40][CH3:41])[cH:31][c:30]([NH2:29])[c:38]([Cl:39])[cH:37]1

参加物

反応物 2

HCID 816264-Amino-5-chloro-2-methoxybenzoic acid

HCID 537857162-(3-(3-tert-butoxycarbonylaminomethylpyrrolidin-1-yl)propyl)-2,3-dihydro-1 H-isoindole-1,3-dione

生成物 1

HCID 540884074-amino-5-chloro-N-(1-(3-(2,3-dihydro-1,3-dioxo-1 H-isoindol-2-yl)propyl)-pyrrolidin-3-ylmethyl)-2-methoxybenzamide

出典と根拠

ORDレコード: ord-5b0c08180f474f5285a14fb771410758
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…